山田 眞二
理学部化学科 教授



[専門分野]

有機化学、合成有機化学、構造有機化学


[主な担当授業科目]

 (学 部) 反応有機化学、合成有機化学、有機化学実験、他
 (大学院) 有機立体化学、物理有機化学、分子反応設計



[主な研究課題]

  1. カチオン-π相互作用を利用する面選択的反応
  2. 立体選択的光付加環化反応
  3. 新規不斉有機触媒の開発と利用
  4. 結晶配列制御と固相反応
  5. ピリジニウムの特性を利用した反応
  6. ねじれ型アミドの合成、構造、反応

詳細:研究概要



[所属学会等]

  日本化学会、有機合成化学協会、American Chemical Society、International Society of Heterocyclic Chemistry


[最近の業績]

論文(一部の論文はタイトルをクリックするとAbstractにジャンプできます)

  1. S. Yamada, “Cation-π Interactions in Organic Crystals”, Coord. Chem. Rev., 2020, 415, 213301.(Celebrating 150 Years from Mendeleev: The Periodic Table of Chemical Interactions).

  2. S. Yamada, K. Aya, “Solid-State [2+2] Photodimerization of 1-Aryl-4-pyridylbutadienes in Cation-π-Controlled Crystals”, Chem. Asian J. , 2020, 15, 581-584. (Special collection for 100th Annual Meeting of the CSJ). DOI: 10.1002/asia.201901707

  3. G. J. Richards, A. Cador, S. Yamada, A. Middleton, W. A. Webre, J. Labuta, P. A. Karr, K. Ariga, F. D’Souza, S. Kahlal, J.-F. Halet, J. P. Hill, “Amphiprotism-Coupled Near-Infrared Emission in Extended Pyrazinacenes Containing Seven Linearly Fused Pyrazine Units”, J. Am. Chem. Soc. , 2019, 141, 19570-19574. DOI: 10.1021/jacs.9b10952

  4. S. Yamada, Y. Oshima, Y. Fujita, S. Tsuzuki, “The tetraalkylammonium-accelerated Norrish-Yang photocyclization of2-substituted acetophenones”, Tetrahedron Lett. 2019, 60, 1543-1546.

  5. S. Yamada, “Cation-π Interactions in Organic Synthesis”, Chem. Rev. 2018, 118, 11353-11432.

  6. K. Noda, R. Masuzaki, Y. Terauchi, S. Yamada, M. Murata, “Novel Maillard Pigment, Furpenthiazinate, Having Furan and Cyclopentathiazine Rings Formed by Acid Hydrolysis of Protein in the Presence of Xylose or by Reaction between Cysteine and Furfural under Strongly Acidic Conditions”, J. Agtic. Food. Chem. 2018, 66, 11414-11421.

  7. S. Yamada, Y. Nojiri, “[2 + 2] Photodimerization of Naphthylvinylpyridines through Cation-π Interactions in Acidic Solution”, Molecules , 2017, 22, 491.

  8. S. Yamada, N. Yamamoto, E. Takamori, “Synthesis of Molecular Seesaw Balances and the Evaluation of Pyridinium−π Interactions”, J. Org. Chem., 2016, 81, 11819-11830.

  9. Richards, G. J.; Ishihara, S.; Labuta, J.; Miklik, D.; Mori, T.; Yamada, S.; Ariga, K.; Hill, J. P. “Fluorescent mesomorphic pyrazinacenes”, J. Mater. Chem. C, 2016, 4, 11514-11523.

  10. S. Yamada, K. Yamagami, S. Oaku, “ [2+2] photodimerization of (E)-styrylthiazoles through cation–π-controlled preorientation”, Tetrahedron Lett., 2016, 57, 2451-2454.

  11. S. Yamada, N. Yamamoto, E. Takamori, “A Molecular Seesaw Balance: Evaluation of Solvent and Counteranion Effects on Pyridinium−π Interactions”, Org. Lett., 2015, 17, 4862-4865.

  12. S. Yamada, N. Sako, K. Yamada, K. Deguchi, T.Shimizu, “Porous organic hydrate crystals: structure and dynamic behaviour of water clusters”, CrystEngComm, 2015, 17, 5629-5633.

  13. K. Noda, S. Yamada, M. Murata, "Isolation, identification, and formation conditions of a novel Maillardyellowish pigment, pyrrolothiazolate", Biosci. Biotechnol. Biochem. 2015, 79, 1350-1355.

  14. S. Yamada, M. Okuda, N. Yamamoto, “Tetrabutylammonium-assisted diastereoselective[6π]-photocyclization of acrylanilides”, Tetrahedron Lett., 2015, 56, 2098–2101.

  15. S. Yamada, A. Katsuki, Y. Nojiri, Y. Tokugawa, “Vapochromism associated with the changes in the molecular arrangement of organic crystals”, CrystEngComm, 2015, 17, 1416–1420.

  16. S. Yamada, Yuka Azuma and Kanae Aya, “[2+2] photodimerization of 1-aryl-4-pyridylbutadienes through cation–π interactions”, Tetrahedron Lett., 2014, 55, 2801-2804

  17. S. Yamada, A. Iwaoka, Y. Fujita and S. Tsuzuki, “Tetraalkylammonium-Templated Stereoselective Norrish–Yang Cyclization”, Org. Lett., 2013, 15, 5994-5997

  18. S. Yamada, M. Kusafuka, M. Sugawara, “[2+2] Photodimerization of bispyridylethylenes by a controlled shift of the protonation equilibrium”, Tetrahedron Lett., 2013, 54, 3997-4000

  19. S. Yamada, N. Sako, M. Okuda and A. Hozumi, “A dual-synthon in pyridinium chloride: formation of ladder-like and columnar motifs through hydrogen bonds and cation–π interactions”, CrystEngComm, 2013, 15, 199-205

  20. S. Yamada and C.Kawamura, “[4+4] Photodimerization of Azaanthracenes in Both Solution and Solid Phase Controlled by Cation-π Interactions”, Org. Lett., 2012, 14, 1572-1575

  21. S. Yamada, Y. Tokugawa, Y. Nojiri and E. Takamori, “Cascade reactions in crystals through cation-π-controlled reorientation on exposure to HCl gas”, Chem. Commun., 2012, 48, 1763-1765

  22. Y. Mori and S. Yamada, “Contribution of Cation-π Interactions in Iminium Catalysis”, Molecules, 2012, 17, 2161-2168

  23. S. Yamada and J. S. Fossey, “Nitrogen cation-π interactions in asymmetric organocatalytic synthesis”, Org. Biomol. Chem., 2011,9, 7257-7580.

  24. S. Yamada and Y. Nojiri, “Water-assisted assembly of (E)-arylvinylpyridine hydrochlorides: effective substrates for solid-state [2+2] photodimerization”, Chem. Commun., 2011,47, 9143-9145.

  25. Nakamura, H. Irie, S. Hara, M. Sugawara and S. Yamada, “Regiospecific [2+2] photocyclodimerization of trans-4-styrylpyridines templated by cucurbit[8]uril”, Photochem. Photobiol. Sci., 2011, 10, 1496-1500.

  26. M. Satoh, Y. Nomi, S. Yamada, M. Takenaka, H. Ono, M. Murata, “Identification of 2,4-dihydroxy-2,5-dimethyl-3(2H)-thiophenone as low-molecular-weight yellow pigment in soy sauce”, Biosci. Biotechnol. Biochem., 2011, 75, 1240-1244.

  27. W. Chen, S. A. Elfeky, Y. Nonne, L. Male, K. Ahmed, C. Amiable, P. Axe, S. Yamada, T. D. James, S. D. Bull and J. S. Fossey, “A pyridinium cation?pi interaction sensor for the fluorescent detection of alkyl halides”, Chem. Commun., 2011,47, 253-255.

  28. S. Yamada and J. S. Fossey, “Nitrogen cation?pi interactions in asymmetric organocatalytic synthesis”, Org. Biomol. Chem., 2011, 9, 7275-7580.

  29. S. Yamada, M. Abe, “Selective deprotection and amidation of 2-pyridyl esters via N-methylation”, Tetrahedron, 2010, 66, 8667-8671.

  30. S. Yamada, Y. Nojiri, M. Sugawara, “[2+2]photodimerization of (Z)-4-styrylpyridine through a cation-π interaction:formation of cis-cis-trans dimers”, Tetrahedron Lett. 2010, 51, 2533-2535.

  31. S. Yamada, Y. Takahashi, “Stereoselective synthesis of N,N-acetals by cyclization of an N-acyliminium ion through interaction with an N-sulfonyl group”, Tetrahedron Lett. 2009, 50, 5395-5398.

  32. A. Shimizu, T. Mori, Y. Inoue, S. Yamada, “Combined Experimental and Quantum Chemical Investigation of Chiroptical Properties of Nicotinamide Derivatives with and without Intramolecular Cation-π Interactions”, J. Phys. Chem., 2009 113, 8754-8764.

  33. S. Yamada, Y. Tokugawa, “Cation-π Controlled Solid-State Photodimerization of 4-Azachalcones”, J. Am. Chem. Soc., 2009, 131, 2098-2099.

  34. S. Yamada, A. Toshimitsu, Y. Takahashi, “A significant substituent effect on the regeoselectivity in addition of alkynes to 3-substituted pyridines”, Tetrahedron, 2009, 65, 2329-2333.

  35. S. Yamada, E. Ohta, “An Unusual Reaction of a Pyridinium Ylide with 1,1-Dicyanoethylene Derivatives”, Chem. Lett., 2008, 37, 628-629.

  36. S. Yamada, E. Ohta, “(1-Pyridinio)perfluorophenacylide: a new stable pyridinium ylide in the enol form”, Acta Cryst., 2008, C64, o230-o232.

  37. S. Yamada, K. Yamashita, “Dynamic Kinetic Resolution of Hemiaminals Using a Novel DMAP Catalyst”, Tetrahedron Lett., 2008, 49, 32-35.

  38. S. Yamada, N. Uematsu, K. Yamashita,“Role of Cation-p Interactions in the Photodimerization of trans-4-Styrylpyridines”, J. Am. Chem. Soc., 2007, 129, 12100-12101.

  39. S. Tsuzuki, M. Mikami and S. Yamada, “Origin of attraction, magnitude and directionality of interactions in benzene complexes with pyridinium cations”, J. Am. Chem. Soc., 2007, 129, 8656-8662.

  40. S. Yamada, M. Inoue, "Regio- and Stereoselective Addition of Allylmetal Reagents to Pyridinium- and Quinolinium-π complexes", Org. Lett., 2007, 9, 1477-1480.

  41. S. Yamada, J. Yamamoto, E. Ohta, "Enantioselective cyclopropanation reaction using a conformationally fixed pyridinium ylide through a cation-π interaction" Tetrahedron Lett., 2007, 48, 855-858.

  42. S. Yamada, “Intramolecular cation-pi interaction in organic synthesis”, Org. Biomol. Chem.(Perspective), 2007, 5, 2903-2912.

  43. S. Yamada, T. Misono, Y. Iwai, A. Masumizu, Y. Akiyama, “A New Class of Pyridine Catalyst Having a Conformation Switch System: Asymmetric Acylation of Various sec-Alcohols” J. Org. Chem., 2006, 71, 6872-6880

  44. S. Yamada, Y. Morimoto, "Two significantly different conformations in crystal: formation of a molecular dimmer governed by cation-π interactions" Tetrahedron Lett., 2006, 46, 5557-5560.

  45. S. Yamada, I. Jahan, "A new route to 3,4-disubstituted piperidines: formal total synthesis of (-)-paroxetine and (+)-femoxetine" Tetrahedron Lett., 2005, 46, 8673-8676.

  46. S. Yamada, Y. Morimoto, T. Misono, "Preference of intra- and intermolecular cation-π interaction: cis-trans geometrical effects of amide bond on the interaction mode" Tetrahedron Lett., 2005, 46, 5673-5676.

  47. S. Yamada, T. Misono and Y. Iwai, "Kinetic resolution of sec-alcohols by a new class of pyridine catalysts having a conformation switch system" Tetrahedron Lett., 2005, 46, 2239-2242.

  48. S. Yamada, C. Morita and J. Yamamoto, "Elucidation of the formation of cation-π complexes and their conformational behavior in solution by CD spectroscopy", Tetrahedron Lett., 2004, 45, 7475-7478.

  49. S. Yamada, T. Misono and S. Tsuzuki, "Cation-p interactions of a Thiocarbonyl Group and a Carbonyl Group With a Pyridinium Nucleus", J. Am. Chem. Soc., 2004, 126, 9862-9872.

  50. S. Yamada, T. Misono, C. Morita and N. Nunami " A novel one-pot, three-component reaction: formation of tricyclic 1,2-dihydropyridines via mesomeric betaines" Tetrahedron Lett., 2003, 44, 7365-7367.

  51. P. Acharya, O. Plashkevych, C. Morita, S. Yamada and J. Chattopadhyaya, "A Repertoire of Pyridinium-Phenyl-Methyl Cross-Talk through a Cascade of Intramolecular Electrostatic Interactions", J. Org. Chem., 2003, 68, 1529-1538.

  52. M. Sharfuddin, A. Narumi, Y. Iwai, K. Miyazawa, S. Yamada, T. Kakuchi and H. Kaga, "Lipase-catalyzed dynamic kinetic resolution of hemiaminals", Tetrahedron: Asymmetry, 2003, 14, 1581-1585.

  53. U. El-Ayaan, A. Paulovicova, S. Yamada and Y. Fukuda, "X-ray Crystal Structure of Bis[N-(2,6-diisopropylphenyl)imino] acenaphthene Ligand and Some Studies Including Its Copper(I) and Copper(II) Complexes" J. Coord. Chem., 2003, 56, 373-381.

  54. S. Yamada and A. Homma, "N-Substituent Effect on the cis-trans Geometry of Nine-Membered Lactams", Chem. Commun., 2002, 2656-2657.

  55. S. Yamada and C. Morita, "Face-selective Addition to a Cation-p Complex of a Pyridinium Salt: Synthesis of Chiral 1,4-Dihydropyridines", J. Am. Chem. Soc., 2002, 124, 8184-8185.

  56. S. Yamada, M. Saitoh and T. Misono, "Stereoselective Synthesis of 1,2- and 1,4-Dihydropyridines by Using Cation-p interaction as a Conformation-Controlling Tool", Tetrahedron Lett., 2002, 43, 5853-5857.

  57. S. Yamada, S. Yaguchi and K. Matsuda, "N-Acylation of Amides with Acid Anhydrides by Way of Dual Activation Using MgBr2・Et2O", Tetrahedron Lett., 2002, 43, 647-651.

  58. S. Yamada, T. Misono, M. Ichikawa and C. Morita, "Regio- and Stereoselective Synthesis of 1,4-Dihydropyridines by way of an Intramolecular Interaction of a Thiocarbonyl or Carbonyl with a Pyridinium Nucleus", Tetrahedron, 2001, 57, 8939-8949.

  59. S. Yamada and C. Morita, "Regio- and Stereoselective Addition of Ketene Silyl Acetals to Quinolinium Salts by Way of an Intramolecular C=O・・・Py+ or C=S・・・Py+ Interaction", Chem. Lett., 2001, 1034-1035.

  60. S. Yamada and T. Misono, "Intra- and Intermolecular Interactions between a Thiocarbonyl Group and a Pyridinium Nucleus" Tetrahedron Lett., 2001, 42, 5497-5500.

  61. S. Yamada and K. Matsuda, "Remarkable Thiocarbonyl and Ring-Size Effects on the Amide Bond Twisting", Chem. Lett., 2001, 750-751.

  62. S. Yamada and E. Noguchi, "Dynamic Kinetic Resolution of Hemiaminals with Axally Chiral Twisted Amide", Tetrahedron Lett., 2001, 42, 3621-3624.

  63. S. Yamada and H. Katsumata, "Asymmetric Acylation of sec-Alcohols with Twisted Amides Possessing Axial Chirality Induced by the Adjacent Chiral Center", J. Org. Chem., 1999, 64, 9365-9373.

  64. S. Yamada and M. Ichikawa, "Synthesis of Chiral 1,4-Dihydropyridines by Diastereoface-selective Asymmetric Addition to Nicotinic Amides", Tetrahedron Lett., 1999, 40, 4231-4234.

  65. S. Yamada, "Chemistry of Highly Twisted Amides", Reviews. on Heteroatom. Chem., 19, 203-236 (1999).

  66. S. Yamada and H. Katsumata, "Desymmetrization of meso-Diols by Acylation with Axially Chiral Twisted Amides and Its Mechanistic Studies", Chem. Lett. 1998, 995-996.

  67. S. Yamada, N. Nunami and K. Hori, "A Nonresonated Orthogonally Twisted Amide" Chem. Lett. 1998, 451-452

  68. S. Yamada, M. Nakamura and I. Kawauchi, "13C-15N Coupling Constants in a Series of Twisted Amides: Relationships with C(O)-N Twist Angles" Chem. Commun. 1997, 885-886.

  69. C. J. Sih, Q.-M. Gu, S. Yamada, F.-J. Zhang, “The chemistry and biology od cyclic-ADP-ribose” Chinese J. Org. Chem., 1997, 17, 43-46.

  70. F-J. Zhang, S. Yamada, Q-M. Gu and C. J. Sih", Synthesis and Characterization of Cyclic ATP-Ribose: A Potent Mediator of Calcium Release" Bioorg. Med. Chem. Lett., 1996, 6, 1203-1208.

  71. S. Yamada and T. Ohe, "Kinetic Resolution of sec-Alcohols with Axially Chiral Twisted Amides" Tetrahedron Lett., 1996, 37, 6777-6780.

  72. S. Yamada, T. Sugaki and K. Matsuzaki "Twisted Amides as Selective Acylating Agents for Hydroxyl Groups under Neutral Conditions: Models for Activated Peptides during Enzymatic Acyl Transfer Reactions" J. Org. Chem., 1996, 61, 5932-5938.

  73. S. Yamada "Effects of C(O)-N Bond Rotation on the 13C, 15N, and 17O NMR Chemical Shifts, and Infrared Carbonyl Absorption in a Series of Twisted Amides" J. Org. Chem., 1996, 61, 941-946.

  74. S. Yamada "Relationship between C(O)-N Twist Angles and 17O NMR Chemical Shifts in a Series of Twisted Amides" Angew. Chem. Int. Ed. Engl., 1995, 34, 1113-1115.

  75. S. Yamada, Q-M. Gu and C. J. Sih, "Cyclic ADP-ribose via Stereoselective Cyclization of β-NAD+", J. Am. Chem. Soc., 1994, 116, 10787-10788.

  76. S. Yamada, H. Ishikawa and M. Matsumoto, “An Unusual Photochemical Extrusion of Carbon Dioxide from Levoglucosenone Derivatives via Carbene Intermediates" J. Chem. Soc. Chem. Commun., 1994, 2155-2156.

  77. S. Yamada, "Structure and Reactivity of a Highly Twisted Amide" Angew. Chem. Int. Ed. Engl., 1993, 32, 1083-1085.

  78. 野宮健司、西本右子、山田眞二、武井尊也「学生実験テーマとしての酸化物高温超伝導体の合成と物性」、化学と教育、40, 612-615 (1992).

  79. S. Yamada, "Selective Pivaloylation of Hydroxyl Group by 3-Pivaloyl-1,3-thiazolidine-2-thione under Neutral Conditions" Tetrahedron Lett., 1992, 33, 2171-2174.

  80. S. Yamada, "Highly Selective Acylation of Di- and Polyhydroxyl Compounds by 3-Pivaloyl-1,3-thiazolidine-2-thione" J. Org. Chem., 1992, 57, 1591-1592.

  81. S. Yamada and M. Matsumoto, "Photochemical α-Cleavage Reaction of Levoglucosenone", Chem. Lett., 1992, 2273-2276.

  82. H. Suginome, M. Kaji, T. Ohtsuka, S. Yamada, T. Ohki, H. Senboku and A. Furusaki, "Novel Stereospecific Photorearrangement and Stereospecific Addition of Methanol in Steroidal α,β-Unsaturated Cyclic Ketone Oximes" J. Chem. Soc., Perkin Trans. 1, 1992, 427-432.

  83. H. Suginome, S. Yamada, and J. B. Wong, "A Versatile Substitution of a Carbonyl Group of Steroidal Ketones by a Heteroatom. The Synthesis of aza-, Oxa-, Thia-, Selena-, and Tellurasteroids" J. Org. Chem., 1990, 55, 2170-2176.

  84. H. Suginome, H. Senboku and S. Yamada, "Transformation of Steroids into Ring-A Aromatized Steroids and 19-Norsteroids involving a Regioselective β-Scission of Alkoxyl Radical", J. Chem. Soc., Perkin Trans. 1, 1990, 2199-2205.

  85. H. Suginome, G. Satoh, J. B. Wang, S. Yamada and K. Kobayashi, "The Fromation of Cyclic Anhydrides via Regioselective β-Scission of Alkoxyl Radical generated from 5- and 6-Membered α-Hydroxy Cyclic Ketones", J. Chem. Soc., Perkin Trans. 1 1990, 1239-1245.

  86. H. Suginome, M. Kaji and S. Yamada, "Regiospecific Photo-Beckmann Rearenge-ment of Steroidal α,β-Unsaturated Ketone Oximes: Synthesis of Some Steroidal Enamino Lactames" J. Chem. Soc., Perkin Trans 1 1988, 321-326.

  87. H. Suginome and S. Yamada, "A Simple New Synthesis of Macrolides by a Consecutive Intramolecular HomoliticAddition-β-Scission of Alkoxyl Radicals. A New Entry to the Synthesis of 15-Pentadecanolide" Chem. Lett. 1988, 245-248.

  88. H. Suginome, H. Senboku and S. Yamada, "A New Aromatization of Steroids. Synthesis of Estrone" Tetrahedron Lett., 29, 79-82 (1988).

  89. H. Suginome and S. Yamada, "Synthesis of Some Five- and Six-Membered Oxasteroids of Cholestane Series by Ring Contraction and the Mass Spectroscopic Fragmentation of Oxasteroids", Bull. Chem. Soc. Jpn. 1987, 60, 2453- 2462.

  90. H. Suginome, M. Kaji, T. Ohtsuka, S. Yamada and A. Furusaki "A New Stereo-specific Rearrangement of an Excited Steroidal α,β-Unsaturated Cyclic Ketone Oxime", J. Chem. Soc., Chem. Commun., 1987, 283-284.

  91. H. Suginome, J. B. Wang and S. Yamada, “Synthesis of Heterosteroids. The First Synthesis of 11-Thiasterolds and a New Synthesis of 11-Oxasteroids”, Chem. Lett., 1987, 738-741.

  92. H. Suginome, H. Washiyama and S. Yamada, "The Transformation of Cyclic Alcohols into Cyclic Acetals through a New Oxygen Atom Insertion by Photolysis in the Presence of Lead Tetraacetate and Iodine", Bull. Chem. Soc. Jpn., 1987, 60, 1071-1083.

  93. H. Suginome and S. Yamada, "A New General Synthesis of Macrocyclic Ketones: A New Entry to the Synthesis of Exaltone and (+)-Muscone" Tetrahedron Lett., 1987, 28, 3963-3966.

  94. H. Suginome and S. Yamada, "New General Synthesis of Medium Ring Lactones via Regioselective β-Scission of Alkoxy Radicals Generated From Catacondenced Lactols" Tetrahedron, 1987, 43, 3371- 3386.

  95. H. Suginome and S. Yamada, "An Efficient New Synthesis of 2-Oxa- and 2-Thia-adamantane" Synthesis, 1986, 741-742.

  96. H. Suginome and S. Yamada, "A Four-Step Substitution of a Carbonyl Group of Steroidal Ketones by an Oxygen Atom: A New Method for the Synthesis of Cyclic Ethers" J. Org. Chem., 1985, 50, 2489- 2494.

  97. H. Suginome and S. Yamada, "New General Synthesis of Medium-Sized Lactones: A New Entry to the Synthesis of (+)-Phoracantholide I" Tetrahedron Lett., 1985, 26, 3715-3718.

  98. H. Suginome and S. Yamada "Replacement of a Carbonyl Group of Camphor by an Oxygen Atom: Synthesis of 1,7,7-trimethyl- 2-oxa-bicyclo[2.2.1]heptane" Bull. Chem. Soc. Jpn., 1985, 58, 3055-3057.

  99. H. Suginome, Y. Seki, S. Yamada, K. Orito and N. Miyaura, "On the Mechanism of the Formation of Oxasteroid via Photo- and Thermally-induced Rearrangement of 3-Hydroxy-Steroid Hypoiodite in the Presence of HgO-I2, An 18O Labelling Study" J. Chem. Soc. Perkin Trans 1, 1985, 1431-1436.

  100. H. Suginome and S. Yamada, “Transformation of Five-(and Six-) Membered Cyclic Alcohols into Five- (and Six-) Membered Cyclic Ethers---A New Method of a Two-Step Transformation of Hydroxy Steroids into Oxasteroids” J. Org. Chem. 1984, 49, 3753-3759.

  101. H. Suginome and S. Yamada "Replacement of a Carbonyl Group of Cyclic Ketones by an Oxygen Atom: A Four-Step Transformation of Cyclic Ketones into Cyclic Ethers" Tetrahedron Lett., 1984, 25, 3995-3998.

  102. H. Suginome and S. Yamada "Replacement of a Carbonyl Group of Cyclic Ketones by a Sulfer or a Nitrogen Atom: A New Method for Transformation of Steroidal Ketones into Thia- or Azasteroids", Chem. Lett. 1984, 2079-2083.

  103. H. Suginome, S. Yamada and N. Miyaura, "Mechanism of the Photo-induced Rearrangement of 5α-Androstan-17β-ol Hypoiodite to 13α- and 13β-Formyloxy-16-iodo-13,16-seco-D-nor-5α-androstane in the Presence of HgO-I2: An 18O Labeling Study" Chem. Lett. 1983, 55-58.

  104. H. Suginome and S. Yamada "Insertion of Oxygen Atom in Steroid Frameworks---A New Method of Transformation of Hydroxysteroid into Oxasteroid" Chem. Lett., 1982, 1233-1236.

総説等

  1. 山田眞二、「ICNI 2019 参加報告」、有機結晶結晶部会ニュースレター、2020, 77.

  2. 山田眞二、“大学と競争原理”, 有機合成化学協会誌(巻頭言), 2014, 72, 757.

  3. 山田眞二、“アンモニウム-π相互作用に基づく立体選択的光増感触媒の開発”、文部科学省科学研究費補助金「新学術研究領域:有機分子触媒,News Letter 2014, No. 32

  4. 山田眞二、“ピリジン誘導体と気体の反応による分子配列変化:カチオン-π相互作用による制御”、日本結晶学会誌、55(1), 63-68 (2013)

  5. 山田眞二、“カチオン−π相互作用に基づく有機触媒設計”、文部科学省科学研究費補助金「新学術研究領域:有機分子触媒, News Letter 2012, No. 9

  6. 山田眞二、“分子を操る新たなツール ?分子間カチオンーπ相互作用を用いる有機合成”、化学、66(4), 74-75 (2011).

  7. 山田眞二、「研究室便り」、有機結晶結晶部会ニュースレター, 2011, 3.

  8. 千葉和義、山田眞二、「五感で掴む分子の世界」、Aroma Research、11、48-51(2010).

  9. 山田眞二、“読書のススメ“、化学、61(10), 44 (2007).

  10. 山田眞二、“ひねりの効いた究極のねじれ型アミド合成“、化学、61(10), 70-71 (2006).

  11. 山田眞二、“カチオンーπ相互作用による立体配座制御と立体選択的反応”、有機合成化学協会誌、63, 339-350 (2005).

  12. 山田眞二、“カチオンーπ相互作用”、有機合成化学協会誌、十字路、63, 377 (2005).

  13. 山田眞二、“「不斉有機触媒」の特集にあたって”、化学と工業、 57, 732 (2004).

  14. 山田眞二、“分子内相互作用による有機分子の立体配座制御と合成的利用”、日本結晶学会誌、44、240-245 (2002).

  15. 山田眞二、“カチオンーπ相互作用を利用するキラルなジヒドロピリジン類の合成”、ファインケミカル、31 (15), 5-20 (2002).

  16. 山田眞二、“進化し続ける不斉アルドール反応:ルイス塩基触媒による活性化”、化学、57, 54-55 (2002).

  17. 山田眞二、“ねじれ型アミドの合成、構造、反応”、有機合成化学協会誌、56, 303-311 (1998).

  18. 山田眞二、“ねじれ型アミド”、有機合成化学協会誌、十字路、56, 328 (1998).

  19. 山田眞二、“プロリンミミックの合成とコンホメーション制御”、化学と工業、51, 1907-1908 (1998).

  20. 山田眞二、“新しい光放出制御型リポソーム”、化学と工業、45, 499-500 (1992).


著書(共著)

  1. Shinji Yamada, 「The Cation-π Interaction」Springer Nature, 2022.

  2. S. Yamada, Onium Ion-Assisted Organic Reactions Through Cation-π Interactions, In Noncovalent Interactions in Catalysis, Ed., K. T. Mahmudov, M. N. Kopylovich, M. F. C. Guedes da Silva, A. J. L. Pombeiro, RSC Publishing. 2018, pp 137-152.

  3. S. Yamada, Synthesis Chiral Dihydropyridine, In New Research on Dihydropyridines, Ed., J. Morales, Nova Science Publishers, Inc. 2016, pp 115-137.

  4. 山田眞二(監修 国武豊喜)「超分子サイエンス&テクノロジー」第1章、第2節(4)「超分子におけるカチオンーπ相互作用」pp28-39, NTS、2009.

  5. 松本正勝、山田眞二、横沢勉 21世紀の化学シリーズ2、「反応有機化学」、朝倉書店、2005.

  6. The Amide Linkage: Selected Structural Aspects in Chemistry, Biochemistry and Materials Science; John Wiley & Sons, Inc.: New York, 2000; chapter 8, pp. 215-246.

[受賞・表彰] 

    第3回有機合成化学協会研究企画賞(1991 有機合成化学協会)

    Tetrahedron Letters Most Cited Paper 2005-2008 Award (Elsevier)

紹会先 : TEL:03-5978-5349;
e-mail : yamada.shinji@ocha.ac.jp




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